Epicardium-to-fat transition in injured heart

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August undefined, 2024

WebSep 17, 2024 · The accumulation of epicardial fat was particularly striking in the HFpEF patients with type 2 diabetes and atrial fibrillation; previous studies have shown increases in the volume of epicardial adipose tissue in these two disorders in the absence of heart failure. 6, 11 Interestingly, van Woerden et al. also noted that epicardial fat was ... WebThe Epicardium as an Endogenous Cell Population for Cardiac Repair. The epicardium is a single-cell layer of mesothelial origin located on the outside of the heart. Intriguingly, …

JDB Free Full-Text Epicardial Origin of Resident Mesenchymal …

WebFeb 19, 2016 · The epicardium is an epithelial monolayer that plays a central role in heart development and the myocardial response to injury. Recent developments in our understanding of epicardial cell biology have revealed this layer to be a dynamic participant in fundamental processes underlying the development of the embryonic ventricles, the … WebFeb 3, 2024 · Cardiac adipose tissues, or the visceral fat of the heart, were previously a relatively neglected component of the heart. ... These results suggest that epithelial-to-mesenchymal transition ... As discussed above, cardiac injuries, such as cryoinjury and MI, can re-activate epicardium and induce EpiAD in post-injury mice [[14, 67, 71]]. braca crnomarkovic

Epicardial differentiation drives fibro-fatty remodeling in ...

WebSep 23, 2024 · Epicardial Contribution to the Developing and Injured Heart: Exploring the Cellular Composition of the Epicardium Epicardial Contribution to the Developing and … WebApr 23, 2014 · The discovery of stem and progenitor cells in the adult mammalian heart has added a vital dimension to the field of cardiac regeneration. Cardiac-resident stem cells … WebApr 4, 2014 · Cardiovascular disease remains the major cause of mortality, and cardiac cell therapy has recently emerged as a paradigm for heart repair. The epicardium is a layer of mesothelial cells covering the heart that during development contributes to different cardiovascular lineages, including cardiomyocytes, but which becomes quiescent after … braca djokic leskovac

JDB Free Full-Text Epicardial Origin of Resident Mesenchymal …

Endocardium Contributes to Cardiac Fat Circulation Research

WebRe-imagining discovery and access to research: grants, datasets, publications, citations, clinical trials, patents and policy documents in one place. WebSep 23, 2024 · The epicardium is an essential cell population during cardiac development. It contributes different cell types to the developing heart through epithelial-to-mesenchymal transition (EMT) and it secretes paracrine factors that support cardiac tissue formation. In the adult heart the epicardium is a qu … bracaci gigiWebJan 29, 2015 · Omental and heart fat had the highest percentage of cells that were expressing Wt1. 1. ... cells in the proepicardium migrate and form a sheet of cells which then cover the surface of the heart forming the epicardium ... Epicardium-to-fat transition in injured heart. Cell Res 2014; 24:1367-9; PMID:25257468; ... braca drinic

"WebSep 26, 2014 · The epicardium is a mesothelial layer that surrounds the heart of all vertebrates and gives rise to multiple cell lineages during heart development and … " - Epicardium-to-fat transition in injured heart

Epicardium-to-fat transition in injured heart

WebOct 28, 2024 · Epicardium-to-fat transition in injured heart. Article. Full-text available. Sep 2014; Qiaozhen Liu; Xiuzhen Huang; Jin-Hee Oh; Bin Zhou; Cell death and differentiation is a monthly research ... WebDOI: 10.1038/cr.2014.125 Corpus ID: 38547720; Epicardium-to-fat transition in injured heart @article{Liu2014EpicardiumtofatTI, title={Epicardium-to-fat transition in injured heart}, author={Qiaozhen Liu and Xiuzhen Huang and Jin-Hee Oh and Ruei-Zeng Lin and Shengzhong Duan and Ying Yu and Rui Yang and Junli Qiu and Juan M. Melero-Martin …

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WebJan 17, 2024 · Whether this epicardial-to-fat transition can occur in the adult heart is being actively investigated. In adult mice overexpressing the adipogenic transcriptional factor peroxisome proliferator-activated … WebThe epicardium, or the innermost layer of the pericardium, is the outermost layer of the heart itself. It is composed of mesothelial cells, fat, and connective tissue. It is adjacent to the myocardium, the middle muscular …

WebJul 31, 2024 · During developmental stages, the epicardium protects and nurtures the underlying myocardium through paracrine signals that promote its growth. 1, 2 The … WebSep 26, 2014 · A recent study showed that mesothelium, including epicardium, contributes to visceral fat 11. Our study of the epicardium confirmed this result and extended it to …

Webprocess as epicardium-to-fat transition (EFT). From this intriguing observation in heart development, we next asked whether adult epicardial progenitors con-tribute to … WebMyocardial injury, high-fat diet, and ANP trigger the adipogenesis process of EPCs and promote the differentiation of EPCs into epicardial adipocytes [8, 9]. However, the ratio of epicardial adipocytes derived from EPCs remained controversial. ... J. H. Oh et al., “Epicardium-to-fat transition in injured heart,” Cell Research, vol. 24, no ...

WebWe refer to this process as epicardium-to-fat transition (EFT). From this intriguing observation in heart development, we next asked whether adult epicardial progenitors …

WebAlthough the epicardium becomes dormant after birth, cardiac injury reactivates developmental gene programs that stimulate epithelial-to … braća đurić mm teslićWebFeb 2, 2015 · In the normal human heart, surface fat (EAT) infiltrates into the myocardium to some degree ( 25 ). At the extreme, however, arrhythmogenic right ventricular … brac adam knappWebEpicardium-to-fat transition in injured heart. Cell Res. 2014; 24: 1367-1369. Crossref; PubMed; Scopus (42) Google Scholar). In contrast, intramyocardial adipocytes are developmentally heterogeneous and originate from both the endocardium and epicardium during embryonic stages ... The transition process of the epicardium to intramyocardial ... braca gaićWebJan 30, 2024 · The heart is lined by a single layer of mesothelial cells called the epicardium that provides important cellular contributions for embryonic heart formation. The epicardium harbors a population of pr braca drinic novi sadWebDec 9, 2015 · Liu Q, Huang X, Oh JH, Lin RZ, Duan S, Yu Y, Yang R, Qiu J, Melero-Martin JM, Pu WT, Zhou B. Epicardium-to-fat transition in injured heart. Cell Res ... The finding of endocardium-to-fat transition has important implications in the cause and pathophysiology of the obesity-associated cardiomyopathy, such as arrhythmogenic right … braca djokovicWebto the epicardium, a sheet of cells covering the surface of heart, revealed that it dynamically participates in both heart development and postnatal heart repair and … braca djukic braca gmbh zeven